Ready to Register?

MyLawCLE All-Access Pass

Best choice

Add the All-Access Pass and get this program —
plus 1,000+ live CLE programs every year.


All specialty & ethics credits included
38 practice areas
New sections: AI & the Law, Practice Management
100s of current and trending legal topics
Nationally recognized and highly experienced presenters

$395 / year — this program included
Register with the All-Access Pass

This program + 1,000+ CLE programs, all year

Or register for just this program

Live Video Broadcast

Live webinar of this one program.
$195 Register

On-Demand Video

Recorded access + self-study credit.
$195 Register

Defending Against Claims Alleging Allergic Hypersensitivity

An allergic reaction is not a defect. Learn to attack causation with dose, route, and threshold-dose science, deploy Rule 12 and preemption motions, challenge plaintiffs’ experts under Rule 702, and carry a science-driven defense theme through trial.

2026-10-14 14:30:00

Program Details

2026-10-14 14:30:00

Program Details

2026-10-14 14:30:00

Over 1,000+ webinars

2026-10-14 14:30:00

Course Overview

An allergic reaction is not a product defect — and the whole case turns on whether you can prove it

2026-10-14 14:30:00

Allergic hypersensitivity claims — contact, respiratory, food, and drug — are being reshaped by recent law. The 2023 amendments to Rule 702 sharpened judicial gatekeeping, and the Supreme Court’s 2026 decision in Monsanto v. Durnell extended labeling preemption from medical devices to EPA-registered products.

The stakes are already concrete. Plead without product-specific facts, and Twiqbal ends the case at Rule 12. Miss the sensitizer-versus-irritant distinction, and the causation record unravels. Skip a threshold-dose assessment, and In re Zantac says the claim should not survive. Overlook Riegel and Durnell, and a preemption defense goes unused.

Attendees leave with phase-by-phase practice pointers from intake to verdict: analyzing the complaint, Rule 12 and preemption motions, discovery aimed at dose and route, deposing and crossing plaintiffs’ experts, Rule 702 and summary judgment briefing, and science-grounded defense themes built for a jury.

Format

CLE Credit

2h CLE Credits

Level

Intermediate

Length

2

Key topics that will be covered

01
Science of Sensitization
How the four hypersensitivity classifications, the sensitizer-versus-irritant distinction, and diagnostic tools — patch, skin-prick, IgE, and oral challenge testing — shape what a litigator must prove or refute.
02
Dose, Route, Threshold
Why dose “makes the poison” in the courtroom: exposure and route analysis, threshold dose under In re Zantac, ADME, and biomarkers as evidence of causation.
03
Claims and Defenses
How strict liability, negligence, failure to warn, design defect, and “hypoallergenic” consumer protection claims fare when the reaction is idiosyncratic — and the affirmative defenses that answer them.
04
Rule 12 and Preemption
How Twiqbal plausibility attacks, judicial notice of FDA materials, the learned intermediary doctrine, and preemption after Riegel and Monsanto v. Durnell can end a case before discovery.
05
General vs. Specific Causation
How epidemiology, dose-response, background risk, the Bradford Hill criteria, differential diagnosis, latency, and Rule 35 genetic testing decide whether a hypersensitivity claim survives.
06
Daubert Through Trial
How to challenge expert testimony under amended Rule 702, win summary judgment, and carry a science-grounded defense theme through jury presentation, cross-examination, and closing argument.

Program schedule

clock 2:30 pm - 3:30 pm EST

Why Allergic Hypersensitivity Cases Are Different: The Science a Litigator Needs, Claims, and Motions Practice

This session opens with why allergic hypersensitivity cases are different: roughly one third of the U.S. population has an allergy, yet the general rule is that the idiosyncratic, hypersensitive, or allergic consumer generally may not recover in a products liability case. It then covers the science a litigator needs — the four classifications of hypersensitivity, sensitizers versus irritants, dose, exposure, and route, threshold dose, ADME, biomarkers, and the tests used to diagnose allergic disease — through real-world case studies including Zurbriggen v. Twin Hill and Cartwright v. Home Depot. The session closes with the causes of action and motions practice that frame these cases: strict liability, negligence, failure to warn, design and manufacturing defect, and consumer protection claims over “hypoallergenic” labels; the principal affirmative defenses; and Rule 12 practice, including Twiqbal plausibility challenges, judicial notice of FDA materials, preemption after Riegel and Monsanto v. Durnell, and the learned intermediary doctrine.

Grant W. HollingsworthGrant W. Hollingsworth
David I. SchifrinDavid I. Schifrin
Joseph F. AltieriJoseph F. Altieri
clock 3:40 pm - 4:40 pm EST

Causation, Rule 702 / Daubert Challenges, Summary Judgment, and Trial Strategy

This session turns to causation — where allergic hypersensitivity claims tend to break down. It works through general versus specific causation; the primary methodologies of epidemiology, dose-response, and background risk; the Bradford Hill criteria; differential diagnosis; latency; and the growing use of genetic testing under Rule 35. The session then addresses Rule 702 / Daubert admissibility challenges to expert testimony in allergic hypersensitivity cases, including the 2023 amendments to Rule 702, recent gatekeeping decisions such as the Acetaminophen MDL and its reversal in Rutledge v. Walgreen, and multiple chemical sensitivity litigation. It concludes with the summary judgment standard and representative decisions, and with trial strategy: developing a persuasive defense theme, presenting complex scientific evidence to a jury, direct and cross-examination of experts, and closing argument.

Grant W. HollingsworthGrant W. Hollingsworth
David I. SchifrinDavid I. Schifrin
Joseph F. AltieriJoseph F. Altieri
Grant W. Hollingsworth

Grant W. Hollingsworth

Hollingsworth LLP

Joseph F. Altieri

Joseph F. Altieri

Hollingsworth LLP

David I. Schifrin

David I. Schifrin

Hollingsworth LLP

Grant W. Hollingsworth

Grant W. Hollingsworth

Hollingsworth LLP

Grant W. Hollingsworth is a partner at Hollingsworth LLP who defends chemical and drug manufacturers in products liability and toxic tort litigation, pairing legal analysis with close work in the underlying scientific data. He develops case themes from detailed review of scientific data and company documents, regularly takes depositions of expert and fact witnesses, prepares witnesses for direct and cross-examination at trial, and handles summary judgment, trial, and appellate advocacy.

Education & Credentials

Mr. Hollingsworth earned his J.D. from Georgetown Law in 2012 and his B.A. from Brown University in 2008. He is admitted to practice in the District of Columbia and Maryland, and before the U.S. Court of Appeals for the Fourth Circuit and the U.S. District Court for the District of Maryland.

Recognition & Leadership

He has been recognized in Chambers USA and named to Super Lawyers for Personal Injury – Products Defense (2026). At the firm, he serves on the Recruitment Committee.

Professional Involvement

His recent writing concentrates on preemption and products liability, including "Depo-Provera Plaintiffs Attempt to Escape Preemption Via Impermissible Expert Testimony" (Daily Business Review, January 2026), "What We're Watching in 2026: Preemption Under Trump 2.0" (February 2026), and "Products Liability Claims Against Digital Platforms Ignore Arbitration Agreements" (June 2026), along with articles for Bloomberg Law and Law360 on arbitration and venue. He is a member of the National Association of Railroad Trial Counsel and attended the National Railroad Trial College.

Experience

Mr. Hollingsworth's matters include the Zometa pharmaceutical products liability cases and In re Tepezza Marketing, Sales Practices, and Products Liability Litigation, in which he helped secure a Rule 12(b)(6) dismissal for Horizon Therapeutics in October 2024. He has represented clients in Department of Justice and Office of Inspector General investigations and in state and federal consumer fraud matters, served as first chair in federal district court, and secured an appellate victory for a sports franchise in Naimoli v. Pro-Football, Inc., 120 F.4th 380 (4th Cir. 2024). Before becoming partner, he was the lead associate on multiple trial teams and clerked in the general counsel's office of Norfolk Southern Corporation.
Joseph F. Altieri

Joseph F. Altieri

Hollingsworth LLP

Joseph F. Altieri is a partner at Hollingsworth LLP who defends multimillion-dollar products liability cases, in which he has served as lead trial associate, argued pre-trial and trial motions, and taken numerous depositions of plaintiffs and treating physicians. His practice centers on distilling the complexities of products liability litigation into clear, persuasive themes for judges and juries. He also has extensive experience preparing and defending corporate and expert witnesses, developing trial strategy, and managing complex pre-trial litigation in high-stakes matters.

Education & Credentials

Mr. Altieri received his J.D., cum laude, from Georgetown Law in 2017, where he was Vice-President of the Student Bar Association and Development Editor of the Journal of Gender and the Law, and received the Alan Goldstein Memorial Award for exceptional client advocacy and a Dean's Certificate for outstanding service to the law school community. He earned his B.B.A., magna cum laude, from the University of Miami in 2009. He is admitted in the District of Columbia and before the U.S. Supreme Court and the U.S. District Court for the District of Columbia.

Recognition & Leadership

He has been named a Super Lawyers Rising Star for Personal Injury – Products Defense each year from 2023 through 2026. At Hollingsworth LLP, he co-chairs the firm's LGBTQ+ employee community group and serves on its recruitment, professional development, and community engagement committees.

Professional Involvement

Mr. Altieri is a member of the American Bar Association, the District of Columbia LGBTQ+ Bar Association, and the National LGBTQ+ Bar Association. His recent work includes a Law360 article on preparing corporate representatives for deposition under Rule 30(b)(6) (November 2025), a CLE webinar panel, "Litigating in Judicial Hellholes in 2025 and Beyond" (November 2025), and an April 2026 presentation on depositions of in-house counsel and the complex legal and ethical issues they raise.

Experience

In major products liability matters, Mr. Altieri has supervised teams of attorneys vetting hundreds of potential experts across scientific disciplines, prepared and defended expert witnesses at deposition, prepared corporate witnesses for deposition and trial testimony, and directed large-scale discovery operations. He previously interned at the U.S. Attorney's Office for the District of Columbia, the Federal Public Defender's Office for the Eastern District of Virginia, and the Superior Court of the District of Columbia, and served as an assistant director of admission at the University of Miami and SUNY.
David I. Schifrin

David I. Schifrin

Hollingsworth LLP

David I. Schifrin is a partner at Hollingsworth LLP who handles pharmaceutical, products liability, and toxic tort matters across the country, with a practice devoted to complex litigation. He is known for thorough factual investigation and for uniting litigation strategy with the specifics of each case. His experience includes managing complex discovery, working closely with expert witnesses, and representing clients in high-stakes product liability litigation.

Education & Credentials

Mr. Schifrin earned his J.D., cum laude, from Georgetown Law in 2017, where he was a staff editor of the Journal of National Security Law & Policy, and his B.A. in Economics, with College Honors, from Washington University in St. Louis in 2013. He is admitted to practice in the District of Columbia, Colorado, Maryland, and Montana.

Recognition & Leadership

Mr. Schifrin has been named a Super Lawyers Rising Star for Civil Litigation Defense three years running (2024, 2025, and 2026). He is recognized for synthesizing complex facts and legal argument into a clear defense strategy and for a proven track record in pharmaceutical, products liability, and toxic tort matters, and his analysis of the defense bar's leading issues — regulatory restrictions in mass tort litigation and the sufficiency of expert testimony — has appeared in For the Defense, Bloomberg Law, and the AmLaw Litigation Daily.

Professional Involvement

Mr. Schifrin is a member of the American Bar Association. His publications include "Navigating Regulatory Bans and Restrictions in Mass Tort Litigation" (For the Defense, October 2025), "Sixth Circuit Tackles Insufficient Expert Testimony in Litigation" (Bloomberg Law, August 2025), and a co-authored AmLaw Litigation Daily article on litigating pesticide bans (September 2024).

Experience

Mr. Schifrin has extensive experience preparing and defending expert witnesses at depositions and trials, helping experts present complex scientific topics in testimony a jury can follow. He manages corporate discovery issues and prepares corporate witnesses to testify in personal and representative capacities. He previously served as a law clerk to the Hon. Anthony C. Epstein of the Superior Court of the District of Columbia and as an Assistant Attorney General in the Civil Litigation Division of the Office of the Attorney General for the District of Columbia.
Grant W. Hollingsworth

Grant W. Hollingsworth

Hollingsworth LLP

Grant W. Hollingsworth is a partner at Hollingsworth LLP who defends chemical and drug manufacturers in products liability and toxic tort litigation, pairing legal analysis with close work in the underlying scientific data. He develops case themes from detailed review of scientific data and company documents, regularly takes depositions of expert and fact witnesses, prepares witnesses for direct and cross-examination at trial, and handles summary judgment, trial, and appellate advocacy.

Education & Credentials

Mr. Hollingsworth earned his J.D. from Georgetown Law in 2012 and his B.A. from Brown University in 2008. He is admitted to practice in the District of Columbia and Maryland, and before the U.S. Court of Appeals for the Fourth Circuit and the U.S. District Court for the District of Maryland.

Recognition & Leadership

He has been recognized in Chambers USA and named to Super Lawyers for Personal Injury – Products Defense (2026). At the firm, he serves on the Recruitment Committee.

Professional Involvement

His recent writing concentrates on preemption and products liability, including "Depo-Provera Plaintiffs Attempt to Escape Preemption Via Impermissible Expert Testimony" (Daily Business Review, January 2026), "What We're Watching in 2026: Preemption Under Trump 2.0" (February 2026), and "Products Liability Claims Against Digital Platforms Ignore Arbitration Agreements" (June 2026), along with articles for Bloomberg Law and Law360 on arbitration and venue. He is a member of the National Association of Railroad Trial Counsel and attended the National Railroad Trial College.

Experience

Mr. Hollingsworth's matters include the Zometa pharmaceutical products liability cases and In re Tepezza Marketing, Sales Practices, and Products Liability Litigation, in which he helped secure a Rule 12(b)(6) dismissal for Horizon Therapeutics in October 2024. He has represented clients in Department of Justice and Office of Inspector General investigations and in state and federal consumer fraud matters, served as first chair in federal district court, and secured an appellate victory for a sports franchise in Naimoli v. Pro-Football, Inc., 120 F.4th 380 (4th Cir. 2024). Before becoming partner, he was the lead associate on multiple trial teams and clerked in the general counsel's office of Norfolk Southern Corporation.
Joseph F. Altieri

Joseph F. Altieri

Hollingsworth LLP

Joseph F. Altieri is a partner at Hollingsworth LLP who defends multimillion-dollar products liability cases, in which he has served as lead trial associate, argued pre-trial and trial motions, and taken numerous depositions of plaintiffs and treating physicians. His practice centers on distilling the complexities of products liability litigation into clear, persuasive themes for judges and juries. He also has extensive experience preparing and defending corporate and expert witnesses, developing trial strategy, and managing complex pre-trial litigation in high-stakes matters.

Education & Credentials

Mr. Altieri received his J.D., cum laude, from Georgetown Law in 2017, where he was Vice-President of the Student Bar Association and Development Editor of the Journal of Gender and the Law, and received the Alan Goldstein Memorial Award for exceptional client advocacy and a Dean's Certificate for outstanding service to the law school community. He earned his B.B.A., magna cum laude, from the University of Miami in 2009. He is admitted in the District of Columbia and before the U.S. Supreme Court and the U.S. District Court for the District of Columbia.

Recognition & Leadership

He has been named a Super Lawyers Rising Star for Personal Injury – Products Defense each year from 2023 through 2026. At Hollingsworth LLP, he co-chairs the firm's LGBTQ+ employee community group and serves on its recruitment, professional development, and community engagement committees.

Professional Involvement

Mr. Altieri is a member of the American Bar Association, the District of Columbia LGBTQ+ Bar Association, and the National LGBTQ+ Bar Association. His recent work includes a Law360 article on preparing corporate representatives for deposition under Rule 30(b)(6) (November 2025), a CLE webinar panel, "Litigating in Judicial Hellholes in 2025 and Beyond" (November 2025), and an April 2026 presentation on depositions of in-house counsel and the complex legal and ethical issues they raise.

Experience

In major products liability matters, Mr. Altieri has supervised teams of attorneys vetting hundreds of potential experts across scientific disciplines, prepared and defended expert witnesses at deposition, prepared corporate witnesses for deposition and trial testimony, and directed large-scale discovery operations. He previously interned at the U.S. Attorney's Office for the District of Columbia, the Federal Public Defender's Office for the Eastern District of Virginia, and the Superior Court of the District of Columbia, and served as an assistant director of admission at the University of Miami and SUNY.
David I. Schifrin

David I. Schifrin

Hollingsworth LLP

David I. Schifrin is a partner at Hollingsworth LLP who handles pharmaceutical, products liability, and toxic tort matters across the country, with a practice devoted to complex litigation. He is known for thorough factual investigation and for uniting litigation strategy with the specifics of each case. His experience includes managing complex discovery, working closely with expert witnesses, and representing clients in high-stakes product liability litigation.

Education & Credentials

Mr. Schifrin earned his J.D., cum laude, from Georgetown Law in 2017, where he was a staff editor of the Journal of National Security Law & Policy, and his B.A. in Economics, with College Honors, from Washington University in St. Louis in 2013. He is admitted to practice in the District of Columbia, Colorado, Maryland, and Montana.

Recognition & Leadership

Mr. Schifrin has been named a Super Lawyers Rising Star for Civil Litigation Defense three years running (2024, 2025, and 2026). He is recognized for synthesizing complex facts and legal argument into a clear defense strategy and for a proven track record in pharmaceutical, products liability, and toxic tort matters, and his analysis of the defense bar's leading issues — regulatory restrictions in mass tort litigation and the sufficiency of expert testimony — has appeared in For the Defense, Bloomberg Law, and the AmLaw Litigation Daily.

Professional Involvement

Mr. Schifrin is a member of the American Bar Association. His publications include "Navigating Regulatory Bans and Restrictions in Mass Tort Litigation" (For the Defense, October 2025), "Sixth Circuit Tackles Insufficient Expert Testimony in Litigation" (Bloomberg Law, August 2025), and a co-authored AmLaw Litigation Daily article on litigating pesticide bans (September 2024).

Experience

Mr. Schifrin has extensive experience preparing and defending expert witnesses at depositions and trials, helping experts present complex scientific topics in testimony a jury can follow. He manages corporate discovery issues and prepares corporate witnesses to testify in personal and representative capacities. He previously served as a law clerk to the Hon. Anthony C. Epstein of the Superior Court of the District of Columbia and as an Assistant Attorney General in the Civil Litigation Division of the Office of the Attorney General for the District of Columbia.

Credits by state

AK2.0
AL2.0
AR2.0
AZ2.0
CA2.0
CO2.0
CT2.0
DC2.0
DE2.0
FL2.0
GA2.0
HI2.0
IA2.0
ID2.0
IL2.0
IN2.0
KS2.0
KY2.0
LA2.0
MA2.0
MD2.0
ME2.0
MI2.0
MN2.0
MO2.4
MS2.0
MT2.0
NC2.0
ND2.0
NE2.0
NH120.0
NJ2.0
NM2.0
NV2.0
NY2.0
OH2.0
OK2.5
OR2.0
PA2.0
RI2.5
SC2.0
SD2.0
TN2.0
TX2.0
UT2.0
VA2.0
VT2.0
WA2.0
WI2.0
WV2.4
WY2.0

1000+

Live stream programs

24/7

Access to live webinars & recordings

70,000+

Trusted by Legal Professionals

1000+

Live stream programs

24/7

Access to live webinars & recordings

70,000+

Trusted by Legal Professionals

1000+

Live stream programs

24/7

Access to live webinars & recordings

10,000+

Trusted by Legal Professionals

1000+

Live stream programs

24/7

Access to live webinars & recordings

70,000+

Trusted by Legal Professionals

MCLE Credits

Alabama
Pending
Alaska
Approved
Arizona
Approved
Arkansas
Approved
California
Approved
Colorado
Pending
Connecticut
Approved
Delaware
Pending
District of Columbia
No Required
Florida
Approved
Georgia
Pending
Hawaii
Approved
Idaho
Pending
Illinois
Pending
Indiana
Pending
Iowa
Pending
Kansas
Pending
Kentucky
Pending
Louisiana
Pending
Maine
Pending
Maryland
No Required
Massachusetts
No Required
Michigan
No Required
Minnesota
Pending
Mississippi
Pending
Missouri
Approved
Montana
Pending
Nebraska
Pending
Nevada
Pending
New Hampshire
Approved
New Jersey
Approved
New Mexico
Approved
New York
Approved
North Carolina
Pending
North Dakota
Approved
Ohio
Pending
Oklahoma
Pending
Oregon
Pending
Pennsylvania
Approved
Rhode Island
Pending
South Carolina
Pending
South Dakota
No Required
Tennessee
Pending
Texas
Approved
Utah
Pending
Vermont
Approved
Virginia
Not Eligible
Washington
Approved
West Virginia
Pending
Wisconsin
Pending
Wyoming
Pending

Alabama

Requirements

The Alabama State Bar MCLE Commission requires attorneys to complete 12 credits, including 1 ethics, by December 31 of each year. All credits must be reported by February 15 of the following year. A maximum of 12 credits, including 1 ethics credit, may be carried over for 1 year only.  

Formats

  • Attorneys can earn unlimited “live” credit through live seminars, live webcasts, and co-sponsored locations with MyLAWCLE-Alabama approved programs
  • Attorneys are limited to 6 credits per compliance period of “online” programs through MyLAwCLE On-Demand programs